Biphenomycins A and B, novel peptide antibiotics. I. Taxonomy, fermentation, isolation and characterization.

نویسندگان

  • M Ezaki
  • M Iwami
  • M Yamashita
  • S Hashimoto
  • T Komori
  • K Umehara
  • Y Mine
  • M Kohsaka
  • H Aoki
  • H Imanaka
چکیده

Biphenomycin A, C23H28N4O8, and biphenomycin B, C23H28N4O7, were isolated from the cultured broth of Streptomyces griseorubiginosus No. 43708. The antibiotics are active in vitro and in vivo against bacteria, and are especially potent against Gram-positive bacteria. The acute toxicity of biphenomycin A is very low in mice.

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 38 11  شماره 

صفحات  -

تاریخ انتشار 1985